Question 2 Define gluconeogenesis and glycogenolysis?
Question 3 Kenchana Singh, a patient with a history of T1DM begins to tremble, feel sweaty and complains of nausea and dizziness. You take her BGL and it is 2.8 mmol/L. Outline the step by step instructions you would provide Kenchana regarding the immediate management of a blood sugar level of 2.8 mmol/L.
Question 4 Explain the following in detail. Pathophysiology of Diabetic Ketoacidosis including how the condition progresses from hyperglycaemia to life-threatening ketoacidosis, fluid and electrolyte imbalance
List the signs and symptoms of DKA including the blood glucose (mmol/L) and bloodketone levels (mmol/L) confirming the diagnosis.
Question 5 Explain the following, in detail. Pathophysiology of Hyperosmolar Hyperglycaemic State including how the condition progresses from hyperglycaemia to life-threatening lactic acidosis, fluid and electrolyte imbalance in the absence of hyperketonaemia
State two causes of HHS
Investigative markers confirming diagnosis i.e. blood glucose level (mmol/L), blood ketone level (mmol/L), Se osmolarity (mOsm/kg) Se bicarbonate level (mmol/L) and clinical presentation
List three management priorities of HHA i.e. the aims of management rather than how it is treated
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